Study Groups


Lead investigator:
Dr Hugh Gallagher, London

Start / End:
2014 - 2017

A programme to spread eGFR graph surveillance for the early identification, support and treatment of people with progressive chronic kidney disease.

This project will roll out an established eGFR graph surveillance intervention intentionally and intelligently to achieve impact at scale. It will implement the intervention in at least 15 pathology laboratories covering 8 main renal units, which serve an estimated total population of 7 to 9 million people. The following overall approach will be adopted:

Work StreamCore Functions

Intervention To refine eGFR graph intervention (including patient-facingelement)
Adoption and Spread To raise awareness of project
To identify and recruit participating sites
To develop and share business cases to secure long-term local funding
Communications activities
Stepped Wedge Delivery and Measurement Quantitative analysis of outcome data
Review of progress against milestones
Management of risks associated with implementation (ensuring alignment between operational delivery of stepped wedge roll-
out and quantitative elements of evaluation)
Stepped Wedge Delivery Quantitative analysis of outcome data
Qualitative Evaluation To perform a qualitative evaluation at level of:
Laboratories/renal units/specialist commissioners (barriers and enablers of adoption, spread and sustainability)
Primary care staff/patients (response “on the ground” to the intervention)

The stepped wedge evaluation will be delivered through collaboration between the School of Health and Related Research (ScHARR) in Sheffield and the UK Renal Registry (UKRR).