Study Groups

EQUAL (European Quality Study)

Lead investigator:
Dr Kitty Jager
Prof Christoph Wanner
Prof Friedo Dekker
Dr Fergus Caskey

Start / End:
2011 - 2016

Project website(s):

The timing of the start of dialysis in elderly patients is driven by the desire to optimise longevity and the quality of life. Limited data exist on how the level of renal function and uraemic signs and symptoms can be used to determine when dialysis should be initiated in elderly patients. EQUAL, an international prospective cohort study, aims to address these issues. To this end it will enrol 4,000 patients older than 65 years of age with Chronic Kidney Disease (CKD) of various aetiology under the care of nephrologists. These patients will be followed until death, discharge from the nephrology clinic to primary care or until the end of the observation period after four years of follow-up. At the time of enrolment, patients must have an estimated GFR of ≤20 ml/min/1.73m2 but should not yet be on dialysis. Standardised data collection will include demographics, lifestyle, comorbidity, uraemic signs and symptoms, nutritional status, medication and routine blood and urine biochemistry. It will also comprise of quality of life data and information on decision making, including patient preferences and patient satisfaction.